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Story file

Genomic history of smallpox in the Americas

The developments in this story so far, most recent first.

  1. Milestone

    How smallpox reached the Americas: first genomic evidence points to Europeans

    No separate article for this desk or language yet.

  2. · date approximate Background

    Smallpox was officially eradicated.

    Smallpox was officially eradicated in 1980.

  3. · date approximate Background

    The first historically documented smallpox outbreak in the Americas occurred during the Spanish conquest of the Caribbean.

    During the Spanish conquest of the Caribbean in 1518, the first historically documented smallpox outbreak occurred in the Americas. The virus, known as Orthopoxvirus variola, was brought to the Americas from Europe.

    The introduction of the disease resulted in millions of deaths across two continents.